A yellow weather warning is in place from Friday afternoon until Saturday evening
People have been warned of travel disruption due to incoming severe gales brought by the first named storm of the season.
Ronaldsway Met Office has issued a yellow weather warning from 16:00 BST on Friday until 18:00 on Saturday, with gusts of up to 65mph (105km/h) expected as Storm Amy hits the island on Friday.
The island's ferry firm has cancelled Friday's Liverpool sailing and brought the morning's sailing to Lancashire forward, with all of Saturday's crossings also affected.
Forecaster have also advised people to be aware of possible on-island disruption due to fallen trees, minor structural damage to properties and flooding on roads due to heavy rain.
The Isle of Man Steam Packet Company has pulled Manxman's crossing to Heysham forward by 30 minutes to 07:30, with the Douglas-bound return running 45 minutes earlier than originally scheduled.
It follows changes to sailings on Thursday due to the weather conditions.
Civil Defence Isle of Man has urged people to tie down or store away garden furniture and remove leaves from drains to help reduce flooding.
Sand bags have also been made available at its headquarters on Tromode Road for those in areas prone to flooding.
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